This is probably going to sound funny, but just starting out with the software the most annoying thing is when I hover over a command after right clicking on a blue/red node, and the yellow description of the commands function only shows for around 5 seconds.
It's especially bothersome when the description is more than a paragraph, you are almost to the end, and then it goes away...
Everything else is great so far, it's just those descriptions need to stay on until I hover off of them.
Otherwise they might as well be turned off ;D